Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection

The world has seen the emergence of a new virus in 2019, SARS-CoV-2, causing the COVID-19 pandemic and millions of deaths worldwide. Microscopy can be much more informative than conventional detection methods such as RT-PCR. This review aims to present the up-to-date microscopy observations in patie...

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Autores principales: Deroubaix, Aurélie, Kramvis, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355083/
https://www.ncbi.nlm.nih.gov/pubmed/35937687
http://dx.doi.org/10.3389/fcimb.2022.794264
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author Deroubaix, Aurélie
Kramvis, Anna
author_facet Deroubaix, Aurélie
Kramvis, Anna
author_sort Deroubaix, Aurélie
collection PubMed
description The world has seen the emergence of a new virus in 2019, SARS-CoV-2, causing the COVID-19 pandemic and millions of deaths worldwide. Microscopy can be much more informative than conventional detection methods such as RT-PCR. This review aims to present the up-to-date microscopy observations in patients, the in vitro studies of the virus and viral proteins and their interaction with their host, discuss the microscopy techniques for detection and study of SARS-CoV-2, and summarize the reagents used for SARS-CoV-2 detection. From basic fluorescence microscopy to high resolution techniques and combined technologies, this article shows the power and the potential of microscopy techniques, especially in the field of virology.
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spelling pubmed-93550832022-08-06 Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection Deroubaix, Aurélie Kramvis, Anna Front Cell Infect Microbiol Cellular and Infection Microbiology The world has seen the emergence of a new virus in 2019, SARS-CoV-2, causing the COVID-19 pandemic and millions of deaths worldwide. Microscopy can be much more informative than conventional detection methods such as RT-PCR. This review aims to present the up-to-date microscopy observations in patients, the in vitro studies of the virus and viral proteins and their interaction with their host, discuss the microscopy techniques for detection and study of SARS-CoV-2, and summarize the reagents used for SARS-CoV-2 detection. From basic fluorescence microscopy to high resolution techniques and combined technologies, this article shows the power and the potential of microscopy techniques, especially in the field of virology. Frontiers Media S.A. 2022-07-22 /pmc/articles/PMC9355083/ /pubmed/35937687 http://dx.doi.org/10.3389/fcimb.2022.794264 Text en Copyright © 2022 Deroubaix and Kramvis https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Deroubaix, Aurélie
Kramvis, Anna
Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection
title Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection
title_full Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection
title_fullStr Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection
title_full_unstemmed Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection
title_short Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection
title_sort imaging techniques: essential tools for the study of sars-cov-2 infection
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355083/
https://www.ncbi.nlm.nih.gov/pubmed/35937687
http://dx.doi.org/10.3389/fcimb.2022.794264
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