Cargando…
Novel computational models offer alternatives to animal testing for assessing eye irritation and corrosion potential of chemicals
Eye irritation and corrosion are fundamental considerations in developing chemicals to be used in or near the eye, from cleaning products to ophthalmic solutions. Unfortunately, animal testing is currently the standard method to identify compounds that cause eye irritation or corrosion. Yet, there i...
Autores principales: | Silva, Arthur C., Borba, Joyce V.V.B., Alves, Vinicius M., Hall, Steven U.S., Furnham, Nicholas, Kleinstreuer, Nicole, Muratov, Eugene, Tropsha, Alexander, Andrade, Carolina Horta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355119/ https://www.ncbi.nlm.nih.gov/pubmed/35935266 http://dx.doi.org/10.1016/j.ailsci.2021.100028 |
Ejemplares similares
-
STopTox: An in Silico Alternative to Animal Testing for Acute Systemic and Topical Toxicity
por: Borba, Joyce V.B., et al.
Publicado: (2022) -
Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization
por: Alves, Vinicius M., et al.
Publicado: (2015) -
Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents
por: Giuliani, Sandra, et al.
Publicado: (2018) -
Computer-Aided Discovery of New Solubility-Enhancing Drug Delivery System
por: Mizera, Mikołaj, et al.
Publicado: (2020) -
Unveiling the Kinomes of Leishmania infantum and L. braziliensis Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds
por: Borba, Joyce V.B., et al.
Publicado: (2019)