Ubiquitination-coupled liquid phase separation regulates the accumulation of the TRIM family of ubiquitin ligases into cytoplasmic bodies

Many members of the tripartite motif (TRIM) family of ubiquitin ligases localize in spherical, membrane-free structures collectively referred to as cytoplasmic bodies (CBs) in a concentration-dependent manner. These CBs may function as aggresome precursors or storage compartments that segregate pote...

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Detalles Bibliográficos
Autores principales: Tozawa, Takafumi, Matsunaga, Kohichi, Izumi, Tetsuro, Shigehisa, Naotake, Uekita, Takamasa, Taoka, Masato, Ichimura, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355226/
https://www.ncbi.nlm.nih.gov/pubmed/35930602
http://dx.doi.org/10.1371/journal.pone.0272700

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