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Sex chromosome aneuploidies give rise to changes in the circular RNA profile: A circular transcriptome-wide study of Turner and Klinefelter syndrome across different tissues

Purpose: The landscape of circular RNAs (circRNAs), an important class of non-coding RNAs that regulate gene expression, has never been described in human disorders of sex chromosome aneuploidies. We profiled circRNAs in Turner syndrome females (45,X; TS) and Klinefelter syndrome males (47,XXY; KS)...

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Detalles Bibliográficos
Autores principales: Johannsen, Emma B., Just, Jesper, Viuff, Mette H., Okholm, Trine Line Hauge, Pedersen, Steen B., Meyer Lauritsen, Katrine, Trolle, Christian, Pedersen, Mette Glavind Bülow, Chang, Simon, Fedder, Jens, Skakkebæk, Anne, Gravholt, Claus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355307/
https://www.ncbi.nlm.nih.gov/pubmed/35938026
http://dx.doi.org/10.3389/fgene.2022.928874