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The human cathelicidin peptide LL-37 inhibits pancreatic cancer growth by suppressing autophagy and reprogramming of the tumor immune microenvironment

Pancreatic cancer is amongst the most lethal malignancies, while its poor prognosis could be associated with promotion of autophagy and the tumor immune microenvironment. Studies have confirmed the pro-tumorigenic nature of the cathelicidin family of peptide LL-37 in several types of cancer. However...

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Detalles Bibliográficos
Autores principales: Zhang, Zhu, Chen, Wen-Qing, Zhang, Shi-Qing, Bai, Jing-Xuan, Lau, Ching-Lam, Sze, Stephen Cho-Wing, Yung, Ken Kin-Lam, Ko, Joshua Ka-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355328/
https://www.ncbi.nlm.nih.gov/pubmed/35935871
http://dx.doi.org/10.3389/fphar.2022.906625