Toward protein NMR at physiological concentrations by hyperpolarized water—Finding and mapping uncharted conformational spaces

Nuclear magnetic resonance (NMR) spectroscopy is a key method for determining the structural dynamics of proteins in their native solution state. However, the low sensitivity of NMR typically necessitates nonphysiologically high sample concentrations, which often limit the relevance of the recorded...

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Detalles Bibliográficos
Autores principales: Epasto, Ludovica M., Che, Kateryna, Kozak, Fanny, Selimovic, Albina, Kadeřávek, Pavel, Kurzbach, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Physical and Materials Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355353/
https://www.ncbi.nlm.nih.gov/pubmed/35930648
http://dx.doi.org/10.1126/sciadv.abq5179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355353/
https://www.ncbi.nlm.nih.gov/pubmed/35930648
http://dx.doi.org/10.1126/sciadv.abq5179

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