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Cryo-EM structures of human hepatitis B and woodchuck hepatitis virus small spherical subviral particles

The loss of detectable hepatitis B surface antigen (HBsAg) is considered a functional cure in chronic hepatitis B. Naturally, HBsAg can be incorporated into the virion envelope or assembled into subviral particles (SVPs) with lipid from host cells. Until now, there has been no detailed structure of...

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Detalles Bibliográficos
Autores principales: Liu, Haitao, Hong, Xupeng, Xi, Ji, Menne, Stephan, Hu, Jianming, Wang, Joseph Che-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355357/
https://www.ncbi.nlm.nih.gov/pubmed/35930632
http://dx.doi.org/10.1126/sciadv.abo4184