Reduced Metabotropic Glutamate Receptor Type 5 Availability in the Epileptogenic Hippocampus: An in vitro Study

Abnormalities in the expression of metabotropic glutamate receptor type 5 (mGluR5) have been observed in the hippocampus of patients with drug-resistant mesial Temporal Lobe Epilepsy (mTLE). Ex-vivo studies in mTLE hippocampal surgical specimens have shown increased mGluR5 immunoreactivity, while in...

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Detalles Bibliográficos
Autores principales: Zimmermann, Maria, Minuzzi, Luciano, Aliaga Aliaga, Arturo, Guiot, Marie-Christine, Hall, Jeffery A., Soucy, Jean-Paul, Massarweh, Gassan, El Mestikawy, Salah, Rosa-Neto, Pedro, Kobayashi, Eliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355376/
https://www.ncbi.nlm.nih.gov/pubmed/35937057
http://dx.doi.org/10.3389/fneur.2022.888479

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