Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition

In some instances, unsuppressed HIV has been associated with severe COVID-19 disease, but the mechanisms underpinning this susceptibility are still unclear. Here, we assessed the impact of HIV infection on the quality and epitope specificity of SARS-CoV-2 T cell responses in the first wave and secon...

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Detalles Bibliográficos
Autores principales: Nkosi, Thandeka, Chasara, Caroline, Papadopoulos, Andrea O, Nguni, Tiza L, Karim, Farina, Moosa, Mahomed-Yunus S, Gazy, Inbal, Jambo, Kondwani, Hanekom, Willem, Sigal, Alex, Ndhlovu, Zaza M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355563/
https://www.ncbi.nlm.nih.gov/pubmed/35880744
http://dx.doi.org/10.7554/eLife.78374

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