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A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins

Signal-anchored (SA) proteins are anchored into the mitochondrial outer membrane (OM) via a single transmembrane segment at their N-terminus while the bulk of the proteins is facing the cytosol. These proteins are encoded by nuclear DNA, translated on cytosolic ribosomes, and are then targeted to th...

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Detalles Bibliográficos
Autores principales: Drwesh, Layla, Heim, Benjamin, Graf, Max, Kehr, Linda, Hansen-Palmus, Lea, Franz-Wachtel, Mirita, Macek, Boris, Kalbacher, Hubert, Buchner, Johannes, Rapaport, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355564/
https://www.ncbi.nlm.nih.gov/pubmed/35876647
http://dx.doi.org/10.7554/eLife.77706

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