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A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins
Signal-anchored (SA) proteins are anchored into the mitochondrial outer membrane (OM) via a single transmembrane segment at their N-terminus while the bulk of the proteins is facing the cytosol. These proteins are encoded by nuclear DNA, translated on cytosolic ribosomes, and are then targeted to th...
Autores principales: | Drwesh, Layla, Heim, Benjamin, Graf, Max, Kehr, Linda, Hansen-Palmus, Lea, Franz-Wachtel, Mirita, Macek, Boris, Kalbacher, Hubert, Buchner, Johannes, Rapaport, Doron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355564/ https://www.ncbi.nlm.nih.gov/pubmed/35876647 http://dx.doi.org/10.7554/eLife.77706 |
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