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Tissue-Agnostic Activity of BRAF plus MEK Inhibitor in BRAF V600–Mutant Tumors

BRAF plus MEK inhibitor combinations are currently FDA-approved for melanoma, non–small cell lung cancer, and anaplastic thyroid cancer. The lack of clinical benefit with BRAF inhibition in BRAF V600–mutated colorectal cancer has prevented its tissue-agnostic drug development. We reviewed the AACR G...

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Detalles Bibliográficos
Autores principales:	Adashek, Jacob J., Menta, Arjun K., Reddy, Neha K., Desai, Aakash P., Roszik, Jason, Subbiah, Vivek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355618/ https://www.ncbi.nlm.nih.gov/pubmed/35413124 http://dx.doi.org/10.1158/1535-7163.MCT-21-0950

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