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Identification of the ubiquitin–proteasome pathway domain by hyperparameter optimization based on a 2D convolutional neural network
The major mechanism of proteolysis in the cytosol and nucleus is the ubiquitin–proteasome pathway (UPP). The highly controlled UPP has an effect on a wide range of cellular processes and substrates, and flaws in the system can lead to the pathogenesis of a number of serious human diseases. Knowledge...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355632/ https://www.ncbi.nlm.nih.gov/pubmed/35937990 http://dx.doi.org/10.3389/fgene.2022.851688 |