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Superselective Ophthalmic Artery Thrombolytic Therapy for Hyaluronic Acid Embolization: A Case Report

Blindness caused by embolization of fillers is a rare but catastrophic complication after cosmetic injection. Vision improvement is rarely reported among the various studies on potential clinical treatments. In this case, the patient suffered from ophthalmic artery occlusion with no light perception...

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Detalles Bibliográficos
Autores principales: Wu, Qian, Fu, Qiang, Xu, Xiao, Zheng, Can, Zhang, Jie, Chen, Minliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355662/
https://www.ncbi.nlm.nih.gov/pubmed/35935598
http://dx.doi.org/10.2147/CCID.S367481
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author Wu, Qian
Fu, Qiang
Xu, Xiao
Zheng, Can
Zhang, Jie
Chen, Minliang
author_facet Wu, Qian
Fu, Qiang
Xu, Xiao
Zheng, Can
Zhang, Jie
Chen, Minliang
author_sort Wu, Qian
collection PubMed
description Blindness caused by embolization of fillers is a rare but catastrophic complication after cosmetic injection. Vision improvement is rarely reported among the various studies on potential clinical treatments. In this case, the patient suffered from ophthalmic artery occlusion with no light perception 48 h after hyaluronic acid injection. After two intra-arterial thrombolytic therapy sessions and traditional sequential therapy, ocular appearance was restored to normal, blood supply to the retina and visual function were improved, and visual acuity was restored to hand motion levels. Our results suggest that intra-arterial thrombolytic therapy with hyaluronidase and papaverine has a positive effect on hyaluronic acid-induced visual loss and is worthy of clinical promotion.
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spelling pubmed-93556622022-08-06 Superselective Ophthalmic Artery Thrombolytic Therapy for Hyaluronic Acid Embolization: A Case Report Wu, Qian Fu, Qiang Xu, Xiao Zheng, Can Zhang, Jie Chen, Minliang Clin Cosmet Investig Dermatol Case Report Blindness caused by embolization of fillers is a rare but catastrophic complication after cosmetic injection. Vision improvement is rarely reported among the various studies on potential clinical treatments. In this case, the patient suffered from ophthalmic artery occlusion with no light perception 48 h after hyaluronic acid injection. After two intra-arterial thrombolytic therapy sessions and traditional sequential therapy, ocular appearance was restored to normal, blood supply to the retina and visual function were improved, and visual acuity was restored to hand motion levels. Our results suggest that intra-arterial thrombolytic therapy with hyaluronidase and papaverine has a positive effect on hyaluronic acid-induced visual loss and is worthy of clinical promotion. Dove 2022-08-01 /pmc/articles/PMC9355662/ /pubmed/35935598 http://dx.doi.org/10.2147/CCID.S367481 Text en © 2022 Wu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Wu, Qian
Fu, Qiang
Xu, Xiao
Zheng, Can
Zhang, Jie
Chen, Minliang
Superselective Ophthalmic Artery Thrombolytic Therapy for Hyaluronic Acid Embolization: A Case Report
title Superselective Ophthalmic Artery Thrombolytic Therapy for Hyaluronic Acid Embolization: A Case Report
title_full Superselective Ophthalmic Artery Thrombolytic Therapy for Hyaluronic Acid Embolization: A Case Report
title_fullStr Superselective Ophthalmic Artery Thrombolytic Therapy for Hyaluronic Acid Embolization: A Case Report
title_full_unstemmed Superselective Ophthalmic Artery Thrombolytic Therapy for Hyaluronic Acid Embolization: A Case Report
title_short Superselective Ophthalmic Artery Thrombolytic Therapy for Hyaluronic Acid Embolization: A Case Report
title_sort superselective ophthalmic artery thrombolytic therapy for hyaluronic acid embolization: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355662/
https://www.ncbi.nlm.nih.gov/pubmed/35935598
http://dx.doi.org/10.2147/CCID.S367481
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