A Phase Ib Study of the Simmitecan Single Agent and in Combination With 5-Fluorouracil/Leucovorin or Thalidomide in Patients With Advanced Solid Tumor

Background: Simmitecan is a potent inhibitor of topoisomerase I with anti-tumor activity. This phase Ib trial was conducted to investigate the safety and anti-tumor effect of simmitecan alone or in combination with other drugs. Methods: Eligible patients with advanced solid tumor had no further stan...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Deng, Ting, Yang, Fen, Guo, Weijian, Liu, Dan, Yuan, Jiajia, Qi, Changsong, Cao, Yanshuo, Yu, Qiuqiong, Cai, Huiming, Peng, Zhi, Wang, Xicheng, Zhou, Jun, Lu, Ming, Gong, Jifang, Li, Jian, Ba, Yi, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355729/
https://www.ncbi.nlm.nih.gov/pubmed/35935841
http://dx.doi.org/10.3389/fphar.2022.833583

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