Cargando…

Low-Intensity Pulsed Ultrasound Enhanced Adipose-Derived Stem Cell-Mediated Angiogenesis in the Treatment of Diabetic Erectile Dysfunction through the Piezo-ERK-VEGF Axis

OBJECTIVES: Erectile dysfunction is a major comorbidity of diabetes. Stem cell transplantation is a promising method to treat diabetic erectile dysfunction. In this study, we evaluated whether low-intensity pulsed ultrasound (LIPUS) could enhance the efficacy of adipose-derived stem cells (ADSCs) an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Shiyun, Jiang, Chenyi, Hu, Jianlin, Chen, Huixing, Han, Bangmin, Xia, Shujie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355763/ https://www.ncbi.nlm.nih.gov/pubmed/35935181 http://dx.doi.org/10.1155/2022/6202842

Ejemplares similares

Periostin promotes tumor angiogenesis in pancreatic cancer via Erk/VEGF signaling
por: Liu, Yang, et al.
Publicado: (2016)

Co‐overexpression of VEGF and GDNF in adipose‐derived stem cells optimizes therapeutic effect in neurogenic erectile dysfunction model
por: Yang, Wende, et al.
Publicado: (2020)

Botanical drugs for treating erectile dysfunction: clinical evidence
por: Xu, Dengjianyi, et al.
Publicado: (2023)

Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling
por: Long, Lingli, et al.
Publicado: (2019)

Therapeutic Angiogenesis as a Potential Future Treatment Strategy for Erectile Dysfunction
por: Ryu, Ji-Kan, et al.
Publicado: (2012)

Hypoxia Precondition Promotes Adipose-Derived Mesenchymal Stem Cells Based Repair of Diabetic Erectile Dysfunction via Augmenting Angiogenesis and Neuroprotection
por: Wang, XiYou, et al.
Publicado: (2015)

Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis
por: Walker, Andrew M N, et al.
Publicado: (2021)

SAIF plays anti-angiogenesis via blocking VEGF-VEGFR2-ERK signal in tumor treatment
por: Xie, Junye, et al.
Publicado: (2023)

ZEB1 Upregulates VEGF Expression and Stimulates Angiogenesis in Breast Cancer
por: Liu, Lingjia, et al.
Publicado: (2016)

GDNF secreted from adipose-derived stem cells stimulates VEGF-independent angiogenesis
por: Zhong, Zhaohui, et al.
Publicado: (2016)

Piezo2 protein: A novel regulator of tumor angiogenesis and hyperpermeability
por: Yang, Hong, et al.
Publicado: (2016)

ORMDL3 Promotes Angiogenesis in Chronic Asthma Through the ERK1/2/VEGF/MMP-9 Pathway
por: Ding, Zhen, et al.
Publicado: (2022)

HDAC10 promotes angiogenesis in endothelial cells through the PTPN22/ERK axis
por: Duan, Baoyu, et al.
Publicado: (2017)

Activation of Piezo1 contributes to matrix stiffness‐induced angiogenesis in hepatocellular carcinoma
por: Li, Miao, et al.
Publicado: (2022)

Oestrogen-induced angiogenesis promotes adenomyosis by activating the Slug-VEGF axis in endometrial epithelial cells
por: Huang, Tze-Sing, et al.
Publicado: (2014)

Nrf2/HO-1 Axis Regulates the Angiogenesis of Gastric Cancer via Targeting VEGF
por: Huang, Yunning, et al.
Publicado: (2021)

Metabolic Syndrome and Erectile Dysfunction: The ultrasound evaluation of cavernosal atherosclerosis
por: Schipilliti, Mirko, et al.
Publicado: (2011)

Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation
por: Mu, Xianmin, et al.
Publicado: (2017)

Inhibition of MMPs supports amoeboid angiogenesis hampering VEGF-targeted therapies via MLC and ERK 1/2 signaling
por: Chillà, Anastasia, et al.
Publicado: (2023)

Low-intensity pulsed ultrasound enhances angiogenesis and ameliorates contractile dysfunction of pressure-overloaded heart in mice
por: Ogata, Tsuyoshi, et al.
Publicado: (2017)

Optimal pulse length of insonification for Piezo1 activation and intracellular calcium response
por: Liao, Defei, et al.
Publicado: (2021)

VEGF tips its hand in angiogenesis
por: Short, Ben
Publicado: (2015)

The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation
por: Zhu, Jiejun, et al.
Publicado: (2023)

Three-Dimensionally Printed Ti2448 With Low Stiffness Enhanced Angiogenesis and Osteogenesis by Regulating Macrophage Polarization via Piezo1/YAP Signaling Axis
por: Tang, Zhen, et al.
Publicado: (2021)

Association between erectile dysfunction and Helicobacter pylori, folic acid, vitamin B12, and homocysteine: a cross-sectional study
por: Xu, Jiangnan, et al.
Publicado: (2023)

Sustained Release of VEGF to Promote Angiogenesis and Osteointegration of Three-Dimensional Printed Biomimetic Titanium Alloy Implants
por: Li, Youbin, et al.
Publicado: (2021)

Erectile Dysfunction
Publicado: (2015)

M-CSF Signals through the MAPK/ERK Pathway via Sp1 to Induce VEGF Production and Induces Angiogenesis In Vivo
por: Curry, Jennifer M., et al.
Publicado: (2008)

PIEZO1 mechanoreceptor activation reduces adipogenesis in perivascular adipose tissue preadipocytes
por: Rendon, C. Javier, et al.
Publicado: (2022)

AB172. Low-intensity pulsed ultrasound recovers erectile function in streptozotocin-induced type I diabetic rats
por: Lei, Hongen, et al.
Publicado: (2015)

LIPUS Promotes Endothelial Differentiation and Angiogenesis of Periodontal Ligament Stem Cells by Activating Piezo1
por: Hu, Rui, et al.
Publicado: (2022)

Harnessing ultrasound in photocatalysis: Synthesis and piezo-enhanced effect: A review
por: Li, Chunyan, et al.
Publicado: (2023)

EGF-Like-Domain-7 Is Required for VEGF-Induced Akt/ERK Activation and Vascular Tube Formation in an Ex Vivo Angiogenesis Assay
por: Takeuchi, Kimio, et al.
Publicado: (2014)

VEGF-Induced Expression of miR-17–92 Cluster in Endothelial Cells Is Mediated by ERK/ELK1 Activation and Regulates Angiogenesis
por: Chamorro-Jorganes, Aránzazu, et al.
Publicado: (2016)

NDRG1 activates VEGF-A-induced angiogenesis through PLCγ1/ERK signaling in mouse vascular endothelial cells
por: Watari, Kosuke, et al.
Publicado: (2020)

Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas
por: Schoedel, Karen, et al.
Publicado: (2021)

Saikosaponin b2 inhibits tumor angiogenesis in liver cancer via down‑regulation of VEGF/ERK/HIF‑1α signaling
por: You, Man, et al.
Publicado: (2023)

The novel VEGF receptor 2 inhibitor YLL545 inhibits angiogenesis and growth in breast cancer
por: Zhang, Jianbo, et al.
Publicado: (2016)

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF
por: Schipani, Ernestina, et al.
Publicado: (2009)

The role of VEGF receptors in angiogenesis; complex partnerships
por: Cébe-Suarez, S., et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_e7gpri9kf47bj3gnjm4p8u1ni9