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Dissociating breathlessness symptoms from mood in asthma

It is poorly understood why asthma symptoms are often discordant with objective medical tests. Differences in interoception (perception of internal bodily processes) may help explain symptom discordance, which may be further influenced by mood and attention. We explored inter-relationships between i...

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Autores principales: Harrison, Olivia K., Marlow, Lucy, Finnegan, Sarah L., Ainsworth, Ben, Pattinson, Kyle T.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355895/
https://www.ncbi.nlm.nih.gov/pubmed/34560173
http://dx.doi.org/10.1016/j.biopsycho.2021.108193
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author Harrison, Olivia K.
Marlow, Lucy
Finnegan, Sarah L.
Ainsworth, Ben
Pattinson, Kyle T.S.
author_facet Harrison, Olivia K.
Marlow, Lucy
Finnegan, Sarah L.
Ainsworth, Ben
Pattinson, Kyle T.S.
author_sort Harrison, Olivia K.
collection PubMed
description It is poorly understood why asthma symptoms are often discordant with objective medical tests. Differences in interoception (perception of internal bodily processes) may help explain symptom discordance, which may be further influenced by mood and attention. We explored inter-relationships between interoception, mood and attention in 63 individuals with asthma and 30 controls. Questionnaires, a breathing-related interoception task, two attention tasks, and standard clinical assessments were performed. Questionnaires were analysed using exploratory factor analysis, and linear regression examined relationships between measures. K-means clustering also defined asthma subgroups. Two concordant asthma subgroups (symptoms related appropriately to pathophysiology, normal mood) and one discordant subgroup (moderate symptoms, minor pathophysiology, low mood) were found. In all participants, negative mood correlated with decreased interoceptive ability and faster reaction times in an attention task. Our findings suggest that interpreting bodily sensations relates to mood, and this effect may be heightened in subgroups of individuals with asthma.
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spelling pubmed-93558952022-08-09 Dissociating breathlessness symptoms from mood in asthma Harrison, Olivia K. Marlow, Lucy Finnegan, Sarah L. Ainsworth, Ben Pattinson, Kyle T.S. Biol Psychol Review It is poorly understood why asthma symptoms are often discordant with objective medical tests. Differences in interoception (perception of internal bodily processes) may help explain symptom discordance, which may be further influenced by mood and attention. We explored inter-relationships between interoception, mood and attention in 63 individuals with asthma and 30 controls. Questionnaires, a breathing-related interoception task, two attention tasks, and standard clinical assessments were performed. Questionnaires were analysed using exploratory factor analysis, and linear regression examined relationships between measures. K-means clustering also defined asthma subgroups. Two concordant asthma subgroups (symptoms related appropriately to pathophysiology, normal mood) and one discordant subgroup (moderate symptoms, minor pathophysiology, low mood) were found. In all participants, negative mood correlated with decreased interoceptive ability and faster reaction times in an attention task. Our findings suggest that interpreting bodily sensations relates to mood, and this effect may be heightened in subgroups of individuals with asthma. Elsevier Science B.V 2021-10 /pmc/articles/PMC9355895/ /pubmed/34560173 http://dx.doi.org/10.1016/j.biopsycho.2021.108193 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Harrison, Olivia K.
Marlow, Lucy
Finnegan, Sarah L.
Ainsworth, Ben
Pattinson, Kyle T.S.
Dissociating breathlessness symptoms from mood in asthma
title Dissociating breathlessness symptoms from mood in asthma
title_full Dissociating breathlessness symptoms from mood in asthma
title_fullStr Dissociating breathlessness symptoms from mood in asthma
title_full_unstemmed Dissociating breathlessness symptoms from mood in asthma
title_short Dissociating breathlessness symptoms from mood in asthma
title_sort dissociating breathlessness symptoms from mood in asthma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355895/
https://www.ncbi.nlm.nih.gov/pubmed/34560173
http://dx.doi.org/10.1016/j.biopsycho.2021.108193
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