Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor

Human spermine oxidase (hSMOX) plays a central role in polyamine catabolism. Due to its association with several pathological processes, including inflammation and cancer, hSMOX has garnered interest as a possible therapeutic target. Therefore, determination of the structure of hSMOX is an important...

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Detalles Bibliográficos
Autores principales: Diaz, Elsie, Adhikary, Suraj, Tepper, Armand W. J. W., Riley, Daniel, Ortiz-Meoz, Rodrigo, Krosky, Daniel, Buyck, Christophe, Lamenca, Carolina Martinez, Llaveria, Josep, Fang, Lichao, Kalin, Jay H., Klaren, Vincent N. A., Fahmy, Shorouk, Shaffer, Paul L., Kirkpatrick, Robert, Carbajo, Rodrigo J., Thomsen, Maren, Impagliazzo, Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355956/
https://www.ncbi.nlm.nih.gov/pubmed/35931745
http://dx.doi.org/10.1038/s42003-022-03735-9

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