Mitoribosome insufficiency in β cells is associated with type 2 diabetes-like islet failure

Genetic variations in mitoribosomal subunits and mitochondrial transcription factors are related to type 2 diabetes. However, the role of islet mitoribosomes in the development of type 2 diabetes has not been determined. We investigated the effects of the mitoribosomal gene on β-cell function and gl...

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Detalles Bibliográficos
Autores principales: Hong, Hyun Jung, Joung, Kyong Hye, Kim, Yong Kyung, Choi, Min Jeong, Kang, Seul Gi, Kim, Jung Tae, Kang, Yea Eun, Chang, Joon Young, Moon, Joon Ho, Jun, Sangmi, Ro, Hyun-Joo, Lee, Yujeong, Kim, Hyeongseok, Park, Jae-Hyung, Kang, Baeki E., Jo, Yunju, Choi, Heejung, Ryu, Dongryeol, Lee, Chul-Ho, Kim, Hail, Park, Kyu-Sang, Kim, Hyun Jin, Shong, Minho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355985/
https://www.ncbi.nlm.nih.gov/pubmed/35804190
http://dx.doi.org/10.1038/s12276-022-00797-x

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