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Exercise-induced FNDC5/irisin protects nucleus pulposus cells against senescence and apoptosis by activating autophagy

Intervertebral disc degeneration (IVDD) is a major cause of low back pain (LBP), and excessive senescence and apoptosis of nucleus pulposus (NP) cells are major pathological changes in IVDD. Physical exercise could effectively delay the process of intervertebral disc degeneration; however, its mecha...

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Detalles Bibliográficos
Autores principales:	Zhou, Wenxian, Shi, Yifeng, Wang, Hui, Chen, Linjie, Yu, Caiyu, Zhang, Xufei, Yang, Lei, Zhang, Xiaolei, Wu, Aimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355987/ https://www.ncbi.nlm.nih.gov/pubmed/35882943 http://dx.doi.org/10.1038/s12276-022-00811-2

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