Pathophysiological evaluation of the LRRK2 G2385R risk variant for Parkinson’s disease

Missense variants in leucine-rich repeat kinase 2 (LRRK2) lead to familial and sporadic Parkinson’s disease (PD). The pathological features of PD patients with LRRK2 variants differ. Here, we report an autopsy case harboring the LRRK2 G2385R, a risk variant for PD occurring mainly in Asian populatio...

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Detalles Bibliográficos
Autores principales: Tezuka, Toshiki, Taniguchi, Daisuke, Sano, Mariko, Shimada, Tomoyo, Oji, Yutaka, Tsunemi, Taiji, Ikeda, Aya, Li, Yuanzhe, Yoshino, Hiroyo, Ogata, Jun, Shiba-Fukushima, Kahori, Funayama, Manabu, Nishioka, Kenya, Imai, Yuzuru, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355991/
https://www.ncbi.nlm.nih.gov/pubmed/35931783
http://dx.doi.org/10.1038/s41531-022-00367-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355991/
https://www.ncbi.nlm.nih.gov/pubmed/35931783
http://dx.doi.org/10.1038/s41531-022-00367-y

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