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Circular RNA ROCK1, a novel circRNA, suppresses osteosarcoma proliferation and migration via altering the miR-532-5p/PTEN axis

As the most prevalent bone tumor in children and adolescents, the pathogenesis and metastasis of osteosarcoma (OS) remain largely unclear. Here, we investigated the expression and function of a novel circular RNA (circRNA), circROCK1-E3/E4, which is back-spliced from exons 3 and 4 of Rho-associated...

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Detalles Bibliográficos
Autores principales: Liu, Yize, Qiu, Guanzhen, Luo, Yinzhou, Li, Shanshan, Xu, Yeqiu, Zhang, Yuanzhuang, Hu, Jiayuan, Li, Peifeng, Pan, Hai, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356001/
https://www.ncbi.nlm.nih.gov/pubmed/35879346
http://dx.doi.org/10.1038/s12276-022-00806-z

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