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Simultaneous regression and classification for drug sensitivity prediction using an advanced random forest method

Machine learning methods trained on cancer cell line panels are intensively studied for the prediction of optimal anti-cancer therapies. While classification approaches distinguish effective from ineffective drugs, regression approaches aim to quantify the degree of drug effectiveness. However, the...

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Detalles Bibliográficos
Autores principales: Lenhof, Kerstin, Eckhart, Lea, Gerstner, Nico, Kehl, Tim, Lenhof, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356072/
https://www.ncbi.nlm.nih.gov/pubmed/35931707
http://dx.doi.org/10.1038/s41598-022-17609-x