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Establishment of autaptic culture with human-induced pluripotent stem cell-derived astrocytes
Although astrocytes are involved in the pathogenesis of CNS diseases, how they induce synaptic abnormalities is unclear. Currently, in vitro pathological astrocyte cultures or animal models do not reproduce human disease phenotypes accurately. Induced pluripotent stem cells (iPSCs) are replacing ani...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356095/ https://www.ncbi.nlm.nih.gov/pubmed/35942096 http://dx.doi.org/10.1016/j.isci.2022.104762 |