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Establishment of autaptic culture with human-induced pluripotent stem cell-derived astrocytes

Although astrocytes are involved in the pathogenesis of CNS diseases, how they induce synaptic abnormalities is unclear. Currently, in vitro pathological astrocyte cultures or animal models do not reproduce human disease phenotypes accurately. Induced pluripotent stem cells (iPSCs) are replacing ani...

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Detalles Bibliográficos
Autores principales: Uchino, Kouya, Tanaka, Yasuyoshi, Kawaguchi, Sayaka, Kubota, Kaori, Watanabe, Takuya, Katsurabayashi, Shutaro, Hirose, Shinichi, Iwasaki, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356095/
https://www.ncbi.nlm.nih.gov/pubmed/35942096
http://dx.doi.org/10.1016/j.isci.2022.104762

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