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Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy

During the period of time between a new disease outbreaks and its vaccine is deployed, the health and the economic systems have to find a testing strategy for reopening activities. In particular, asymptomatic individuals, who transmit locally the COVID-19 indoors, have to be identified and isolated....

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Autores principales: Lugo, Igor, Alatriste-Contreras, Martha G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356132/
https://www.ncbi.nlm.nih.gov/pubmed/35931726
http://dx.doi.org/10.1038/s41598-022-17665-3
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author Lugo, Igor
Alatriste-Contreras, Martha G.
author_facet Lugo, Igor
Alatriste-Contreras, Martha G.
author_sort Lugo, Igor
collection PubMed
description During the period of time between a new disease outbreaks and its vaccine is deployed, the health and the economic systems have to find a testing strategy for reopening activities. In particular, asymptomatic individuals, who transmit locally the COVID-19 indoors, have to be identified and isolated. We proposed a 2D cellular automaton based on the SI epidemic model for selecting the most desirable testing frequency and identifying the best fitting size of random trails on local urban environments to diagnose SARS-CoV-2 and isolate infected people. We used the complex systems approach to face the challenge of a large-scale test strategy based on urban interventions, starting with first responders and essential workers. We used the case of Mexico to exemplify a credible and intelligent intervention that reduces the virus transmission and detects economic and health costs. Findings suggest that controlling and stopping the virus transmission in a short period of time are possible if the frequency of testing is daily and the percentage of random samples to be tested is at least 90%. This combination of model parameters represents the least expensive intervention compared to others. Therefore, the key for a national testing-isolating strategy is local interventions.
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spelling pubmed-93561322022-08-07 Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy Lugo, Igor Alatriste-Contreras, Martha G. Sci Rep Article During the period of time between a new disease outbreaks and its vaccine is deployed, the health and the economic systems have to find a testing strategy for reopening activities. In particular, asymptomatic individuals, who transmit locally the COVID-19 indoors, have to be identified and isolated. We proposed a 2D cellular automaton based on the SI epidemic model for selecting the most desirable testing frequency and identifying the best fitting size of random trails on local urban environments to diagnose SARS-CoV-2 and isolate infected people. We used the complex systems approach to face the challenge of a large-scale test strategy based on urban interventions, starting with first responders and essential workers. We used the case of Mexico to exemplify a credible and intelligent intervention that reduces the virus transmission and detects economic and health costs. Findings suggest that controlling and stopping the virus transmission in a short period of time are possible if the frequency of testing is daily and the percentage of random samples to be tested is at least 90%. This combination of model parameters represents the least expensive intervention compared to others. Therefore, the key for a national testing-isolating strategy is local interventions. Nature Publishing Group UK 2022-08-05 /pmc/articles/PMC9356132/ /pubmed/35931726 http://dx.doi.org/10.1038/s41598-022-17665-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lugo, Igor
Alatriste-Contreras, Martha G.
Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy
title Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy
title_full Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy
title_fullStr Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy
title_full_unstemmed Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy
title_short Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy
title_sort intervention strategies with 2d cellular automata for testing sars-cov-2 and reopening the economy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356132/
https://www.ncbi.nlm.nih.gov/pubmed/35931726
http://dx.doi.org/10.1038/s41598-022-17665-3
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