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The deubiquitinase USP7 promotes HNSCC progression via deubiquitinating and stabilizing TAZ

Dysregulated abundance, location and transcriptional output of Hippo signaling effector TAZ have been increasingly linked to human cancers including head neck squamous cell carcinoma (HNSCC). TAZ is subjected to ubiquitination and degradation mediated by E3 ligase β-TRCP. However, the deubiquitinati...

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Detalles Bibliográficos
Autores principales:	Li, Jin, Dai, Yibin, Ge, Han, Guo, Songsong, Zhang, Wei, Wang, Yanling, Liu, Laikui, Cheng, Jie, Jiang, Hongbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356134/ https://www.ncbi.nlm.nih.gov/pubmed/35931679 http://dx.doi.org/10.1038/s41419-022-05113-z

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