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A pro-inflammatory and fibrous cap thinning transcriptome profile accompanies carotid plaque rupture leading to stroke

Atherosclerotic plaque rupture is the etiology of ischemic stroke and myocardial infarction. The molecular mechanisms responsible for rupture remain unclear, in part, due to the lack of data from plaques at the time of rupture. Ribosome-depleted total RNA was sequenced from carotid plaques obtained...

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Detalles Bibliográficos
Autores principales: Bazan, Hernan A., Brooks, Ashton J., Vongbunyong, Kenny, Tee, Christin, Douglas, Hunter F., Klingenberg, Natasha C., Woods, T. Cooper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356141/
https://www.ncbi.nlm.nih.gov/pubmed/35931792
http://dx.doi.org/10.1038/s41598-022-17546-9

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