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Analysis of germline-driven ancestry-associated gene expression in cancers

Differential mRNA expression between ancestry groups can be explained by both genetic and environmental factors. We outline a computational workflow to determine the extent to which germline genetic variation explains cancer-specific molecular differences across ancestry groups. Using multi-omics da...

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Detalles Bibliográficos
Autores principales: Chambwe, Nyasha, Sayaman, Rosalyn W., Hu, Donglei, Huntsman, Scott, Kemal, Anab, Caesar-Johnson, Samantha, Zenklusen, Jean C., Ziv, Elad, Beroukhim, Rameen, Cherniack, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356164/
https://www.ncbi.nlm.nih.gov/pubmed/35942349
http://dx.doi.org/10.1016/j.xpro.2022.101586

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