Cargando…
Analysis of germline-driven ancestry-associated gene expression in cancers
Differential mRNA expression between ancestry groups can be explained by both genetic and environmental factors. We outline a computational workflow to determine the extent to which germline genetic variation explains cancer-specific molecular differences across ancestry groups. Using multi-omics da...
Autores principales: | Chambwe, Nyasha, Sayaman, Rosalyn W., Hu, Donglei, Huntsman, Scott, Kemal, Anab, Caesar-Johnson, Samantha, Zenklusen, Jean C., Ziv, Elad, Beroukhim, Rameen, Cherniack, Andrew D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356164/ https://www.ncbi.nlm.nih.gov/pubmed/35942349 http://dx.doi.org/10.1016/j.xpro.2022.101586 |
Ejemplares similares
-
Integrative modeling identifies genetic ancestry-associated molecular correlates in human cancer
por: Robertson, A. Gordon, et al.
Publicado: (2021) -
Analytical protocol to identify local ancestry-associated molecular features in cancer
por: Carrot-Zhang, Jian, et al.
Publicado: (2021) -
Analytic pipelines to assess the relationship between immune response and germline genetics in human tumors
por: Sayaman, Rosalyn W., et al.
Publicado: (2022) -
Ancestry-specific predisposing germline variants in cancer
por: Oak, Ninad, et al.
Publicado: (2020) -
Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestry
por: Roelands, Jessica, et al.
Publicado: (2021)