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Cyclin-dependent Kinase 9 as a Potential Target for Anti-TNF-resistant Inflammatory Bowel Disease

BACKGROUND & AIMS: Resistance to single cytokine blockade, namely anti-tumor necrosis factor (TNF) therapy, is a growing concern for patients with inflammatory bowel disease (IBD). The transcription factor T-bet is a critical regulator of intestinal homeostasis, is genetically linked to mucosal...

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Detalles Bibliográficos
Autores principales:	Omer, Omer S., Hertweck, Arnulf, Roberts, Luke B., Lo, Jonathan W., Clough, Jennie N., Jackson, Ian, Pantazi, Eirini D., Irving, Peter M., MacDonald, Tom T., Pavlidis, Polychronis, Jenner, Richard G., Lord, Graham M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356186/ https://www.ncbi.nlm.nih.gov/pubmed/35660024 http://dx.doi.org/10.1016/j.jcmgh.2022.05.011

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