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Sorting through the extensive and confusing roles of sortilin in metabolic disease

Sortilin is a post-Golgi trafficking receptor homologous to the yeast vacuolar protein sorting receptor 10 (VPS10). The VPS10 motif on sortilin is a 10-bladed β-propeller structure capable of binding more than 50 proteins, covering a wide range of biological functions including lipid and lipoprotein...

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Detalles Bibliográficos
Autores principales:	Mitok, Kelly A., Keller, Mark P., Attie, Alan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356209/ https://www.ncbi.nlm.nih.gov/pubmed/35724703 http://dx.doi.org/10.1016/j.jlr.2022.100243

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