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Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male
Pfizer-BioNTech COVID-19 (BNT162b2) conferred a high level of protection against Covid-19 with a proven short-term safety profile. Although cases of vaccine-associated myopericarditis have been reported, the existence of rhabdomyolysis without myocarditis has not yet been published. A 16-year-old, h...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Medical Association Of Malawi
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356520/ https://www.ncbi.nlm.nih.gov/pubmed/35991822 http://dx.doi.org/10.4314/mmj.v34i2.13 |
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author | Sutcu, Murat Gul, Doruk Atik, Fatih Kara, Manolya |
author_facet | Sutcu, Murat Gul, Doruk Atik, Fatih Kara, Manolya |
author_sort | Sutcu, Murat |
collection | PubMed |
description | Pfizer-BioNTech COVID-19 (BNT162b2) conferred a high level of protection against Covid-19 with a proven short-term safety profile. Although cases of vaccine-associated myopericarditis have been reported, the existence of rhabdomyolysis without myocarditis has not yet been published. A 16-year-old, healthy male patient, who did not use any herbal or illegal drugs before, was admitted with muscle pain that developed after the second dose of BNT162b2 vaccine. Cardiac examination and heart enzymes were normal and the patient had significantly higher creatinine kinase levels. The patient, whose enzymes returned to normal with only force hydration therapy, recovered without complications. Reporting the side effects of the vaccine, which has a short history of application to large populations, is of vital importance in the conduct of vaccine development studies and in identifying the risky group in terms of side effects. |
format | Online Article Text |
id | pubmed-9356520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Medical Association Of Malawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-93565202022-08-18 Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male Sutcu, Murat Gul, Doruk Atik, Fatih Kara, Manolya Malawi Med J Brief Report Pfizer-BioNTech COVID-19 (BNT162b2) conferred a high level of protection against Covid-19 with a proven short-term safety profile. Although cases of vaccine-associated myopericarditis have been reported, the existence of rhabdomyolysis without myocarditis has not yet been published. A 16-year-old, healthy male patient, who did not use any herbal or illegal drugs before, was admitted with muscle pain that developed after the second dose of BNT162b2 vaccine. Cardiac examination and heart enzymes were normal and the patient had significantly higher creatinine kinase levels. The patient, whose enzymes returned to normal with only force hydration therapy, recovered without complications. Reporting the side effects of the vaccine, which has a short history of application to large populations, is of vital importance in the conduct of vaccine development studies and in identifying the risky group in terms of side effects. The Medical Association Of Malawi 2022-06 /pmc/articles/PMC9356520/ /pubmed/35991822 http://dx.doi.org/10.4314/mmj.v34i2.13 Text en © 2022 The College of Medicine and the Medical Association of Malawi. https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ) |
spellingShingle | Brief Report Sutcu, Murat Gul, Doruk Atik, Fatih Kara, Manolya Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male |
title | Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male |
title_full | Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male |
title_fullStr | Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male |
title_full_unstemmed | Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male |
title_short | Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male |
title_sort | rhabdomyolysis after bnt162b2 mrna covid-19 vaccine in an adolescent male |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356520/ https://www.ncbi.nlm.nih.gov/pubmed/35991822 http://dx.doi.org/10.4314/mmj.v34i2.13 |
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