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Decrease in CD8(+)CD45(+)CCR7(+)CD62L(+) T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection

Vaccines induce antibodies, but T cell responses are also important for protection against Coronavirus disease 2019. Here, we analyzed the frequency of memory T cells in infected and/or vaccinated individuals and observed a decrease in central memory T cells in individuals who were vaccinated follow...

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Autores principales: Fonseca, Dâmaris C.S.C., Rocha, Mirtes C.B., Pereira, Lucca A., Botega, Leticia P., Cutrim, Susanne C.P.F., Silva, Fabiano V., Batista, Flávio D., Rêgo, Adriana S., Falcai, Ângela, Lima-Neto, Lídio G., Santos, Ana Paula S.A., Carvalho, Rafael C., Sousa, Eduardo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356635/
https://www.ncbi.nlm.nih.gov/pubmed/35944882
http://dx.doi.org/10.1016/j.clim.2022.109092
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author Fonseca, Dâmaris C.S.C.
Rocha, Mirtes C.B.
Pereira, Lucca A.
Botega, Leticia P.
Cutrim, Susanne C.P.F.
Silva, Fabiano V.
Batista, Flávio D.
Rêgo, Adriana S.
Falcai, Ângela
Lima-Neto, Lídio G.
Santos, Ana Paula S.A.
Carvalho, Rafael C.
Sousa, Eduardo M.
author_facet Fonseca, Dâmaris C.S.C.
Rocha, Mirtes C.B.
Pereira, Lucca A.
Botega, Leticia P.
Cutrim, Susanne C.P.F.
Silva, Fabiano V.
Batista, Flávio D.
Rêgo, Adriana S.
Falcai, Ângela
Lima-Neto, Lídio G.
Santos, Ana Paula S.A.
Carvalho, Rafael C.
Sousa, Eduardo M.
author_sort Fonseca, Dâmaris C.S.C.
collection PubMed
description Vaccines induce antibodies, but T cell responses are also important for protection against Coronavirus disease 2019. Here, we analyzed the frequency of memory T cells in infected and/or vaccinated individuals and observed a decrease in central memory T cells in individuals who were vaccinated following COVID-19 infection.
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spelling pubmed-93566352022-08-07 Decrease in CD8(+)CD45(+)CCR7(+)CD62L(+) T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection Fonseca, Dâmaris C.S.C. Rocha, Mirtes C.B. Pereira, Lucca A. Botega, Leticia P. Cutrim, Susanne C.P.F. Silva, Fabiano V. Batista, Flávio D. Rêgo, Adriana S. Falcai, Ângela Lima-Neto, Lídio G. Santos, Ana Paula S.A. Carvalho, Rafael C. Sousa, Eduardo M. Clin Immunol Letter to the Editor Vaccines induce antibodies, but T cell responses are also important for protection against Coronavirus disease 2019. Here, we analyzed the frequency of memory T cells in infected and/or vaccinated individuals and observed a decrease in central memory T cells in individuals who were vaccinated following COVID-19 infection. Elsevier Inc. 2022-09 2022-08-06 /pmc/articles/PMC9356635/ /pubmed/35944882 http://dx.doi.org/10.1016/j.clim.2022.109092 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to the Editor
Fonseca, Dâmaris C.S.C.
Rocha, Mirtes C.B.
Pereira, Lucca A.
Botega, Leticia P.
Cutrim, Susanne C.P.F.
Silva, Fabiano V.
Batista, Flávio D.
Rêgo, Adriana S.
Falcai, Ângela
Lima-Neto, Lídio G.
Santos, Ana Paula S.A.
Carvalho, Rafael C.
Sousa, Eduardo M.
Decrease in CD8(+)CD45(+)CCR7(+)CD62L(+) T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection
title Decrease in CD8(+)CD45(+)CCR7(+)CD62L(+) T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection
title_full Decrease in CD8(+)CD45(+)CCR7(+)CD62L(+) T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection
title_fullStr Decrease in CD8(+)CD45(+)CCR7(+)CD62L(+) T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection
title_full_unstemmed Decrease in CD8(+)CD45(+)CCR7(+)CD62L(+) T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection
title_short Decrease in CD8(+)CD45(+)CCR7(+)CD62L(+) T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection
title_sort decrease in cd8(+)cd45(+)ccr7(+)cd62l(+) t cells in individuals vaccinated with sinovac-coronavac following covid-19 infection
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356635/
https://www.ncbi.nlm.nih.gov/pubmed/35944882
http://dx.doi.org/10.1016/j.clim.2022.109092
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