Treatment With a Three-Drug Regimen for Pulmonary Tuberculosis Based on Rapid Molecular Detection of Isoniazid Resistance: A Noninferiority Randomized Trial (FAST-TB)

BACKGROUND: The rationale behind the use of ethambutol in the standard tuberculosis treatment is to prevent the emergence of resistance to rifampicin in case of primary resistance to isoniazid. We evaluated whether early detection of isoniazid resistance using molecular testing allows the use an eth...

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Detalles Bibliográficos
Autores principales: De Castro, N, Mechaï, F, Bachelet, D, Canestri, A, Joly, V, Vandenhende, M, Boutoille, D, Kerjouan, M, Veziris, N, Molina, J M, Grall, N, Tattevin, P, Laouénan, C, Yazdanpanah, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356674/
https://www.ncbi.nlm.nih.gov/pubmed/35949399
http://dx.doi.org/10.1093/ofid/ofac353

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