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Accounting for Errors in Data Improves Divergence Time Estimates in Single-cell Cancer Evolution

Single-cell sequencing provides a new way to explore the evolutionary history of cells. Compared to traditional bulk sequencing, where a population of heterogeneous cells is pooled to form a single observation, single-cell sequencing isolates and amplifies genetic material from individual cells, the...

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Detalles Bibliográficos
Autores principales: Chen, Kylie, Moravec, Jiří C, Gavryushkin, Alex, Welch, David, Drummond, Alexei J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356729/
https://www.ncbi.nlm.nih.gov/pubmed/35733333
http://dx.doi.org/10.1093/molbev/msac143