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Effect of PFKFB4 on the Prognosis and Immune Regulation of NSCLC and Its Mechanism
BACKGROUND: NSCLC (non-small cell lung cancer) has become the malignancy with the highest incidence and mortality rate worldwide. Fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is a key regulator of glycolysis with both kinase and phosphatase activities. The Warburg effect, or...
Autores principales: | Zhou, Yong, Fan, Yongfei, Qiu, Binzhe, Lou, Ming, Liu, Xiaoshuang, Yuan, Kai, Tong, Jichun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356739/ https://www.ncbi.nlm.nih.gov/pubmed/35942289 http://dx.doi.org/10.2147/IJGM.S369126 |
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