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Effect of PFKFB4 on the Prognosis and Immune Regulation of NSCLC and Its Mechanism

BACKGROUND: NSCLC (non-small cell lung cancer) has become the malignancy with the highest incidence and mortality rate worldwide. Fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is a key regulator of glycolysis with both kinase and phosphatase activities. The Warburg effect, or...

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Detalles Bibliográficos
Autores principales: Zhou, Yong, Fan, Yongfei, Qiu, Binzhe, Lou, Ming, Liu, Xiaoshuang, Yuan, Kai, Tong, Jichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356739/
https://www.ncbi.nlm.nih.gov/pubmed/35942289
http://dx.doi.org/10.2147/IJGM.S369126

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