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A Review on Recent Advances of Cerebral Palsy

This narrative review summarizes the latest advances in cerebral palsy and identifies where more research is required. Several studies on cerebral palsy were analyzed to generate a general idea of the prevalence of, risk factors associated with, and classification of cerebral palsy (CP). Different c...

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Autores principales: Paul, Sudip, Nahar, Anjuman, Bhagawati, Mrinalini, Kunwar, Ajaya Jang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356840/
https://www.ncbi.nlm.nih.gov/pubmed/35941906
http://dx.doi.org/10.1155/2022/2622310
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author Paul, Sudip
Nahar, Anjuman
Bhagawati, Mrinalini
Kunwar, Ajaya Jang
author_facet Paul, Sudip
Nahar, Anjuman
Bhagawati, Mrinalini
Kunwar, Ajaya Jang
author_sort Paul, Sudip
collection PubMed
description This narrative review summarizes the latest advances in cerebral palsy and identifies where more research is required. Several studies on cerebral palsy were analyzed to generate a general idea of the prevalence of, risk factors associated with, and classification of cerebral palsy (CP). Different classification systems used for the classification of CP on a functional basis were also analyzed. Diagnosis systems used along with the prevention techniques were discussed. State-of-the-art treatment strategies for CP were also analyzed. Statistical distribution was performed based on the selected studies. Prevalence was found to be 2-3/1000 lives; the factors that can be correlated are gestational age and birth weight. The risk factors identified were preconception, prenatal, perinatal, and postnatal categories. According to the evidence, CP is classified into spastic (80%), dyskinetic (15%), and ataxic (5%) forms. Diagnosis approaches were based on clinical investigation and neurological examinations that include magnetic resonance imaging (MRI), biomarkers, and cranial ultrasound. The treatment procedures found were medical and surgical interventions, physiotherapy, occupational therapy, umbilical milking, nanomedicine, and stem cell therapy. Technological advancements in CP were also discussed. CP is the most common neuromotor disability with a prevalence of 2-3/1000 lives. The highest contributing risk factor is prematurity and being underweight. Several preventions and diagnostic techniques like MRI and ultrasound were being used. Treatment like cord blood treatment nanomedicine and stem cell therapy needs to be investigated further in the future to apply in clinical practice. Future studies are indicated in the context of technological advancements among cerebral palsy children.
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spelling pubmed-93568402022-08-07 A Review on Recent Advances of Cerebral Palsy Paul, Sudip Nahar, Anjuman Bhagawati, Mrinalini Kunwar, Ajaya Jang Oxid Med Cell Longev Review Article This narrative review summarizes the latest advances in cerebral palsy and identifies where more research is required. Several studies on cerebral palsy were analyzed to generate a general idea of the prevalence of, risk factors associated with, and classification of cerebral palsy (CP). Different classification systems used for the classification of CP on a functional basis were also analyzed. Diagnosis systems used along with the prevention techniques were discussed. State-of-the-art treatment strategies for CP were also analyzed. Statistical distribution was performed based on the selected studies. Prevalence was found to be 2-3/1000 lives; the factors that can be correlated are gestational age and birth weight. The risk factors identified were preconception, prenatal, perinatal, and postnatal categories. According to the evidence, CP is classified into spastic (80%), dyskinetic (15%), and ataxic (5%) forms. Diagnosis approaches were based on clinical investigation and neurological examinations that include magnetic resonance imaging (MRI), biomarkers, and cranial ultrasound. The treatment procedures found were medical and surgical interventions, physiotherapy, occupational therapy, umbilical milking, nanomedicine, and stem cell therapy. Technological advancements in CP were also discussed. CP is the most common neuromotor disability with a prevalence of 2-3/1000 lives. The highest contributing risk factor is prematurity and being underweight. Several preventions and diagnostic techniques like MRI and ultrasound were being used. Treatment like cord blood treatment nanomedicine and stem cell therapy needs to be investigated further in the future to apply in clinical practice. Future studies are indicated in the context of technological advancements among cerebral palsy children. Hindawi 2022-07-30 /pmc/articles/PMC9356840/ /pubmed/35941906 http://dx.doi.org/10.1155/2022/2622310 Text en Copyright © 2022 Sudip Paul et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Paul, Sudip
Nahar, Anjuman
Bhagawati, Mrinalini
Kunwar, Ajaya Jang
A Review on Recent Advances of Cerebral Palsy
title A Review on Recent Advances of Cerebral Palsy
title_full A Review on Recent Advances of Cerebral Palsy
title_fullStr A Review on Recent Advances of Cerebral Palsy
title_full_unstemmed A Review on Recent Advances of Cerebral Palsy
title_short A Review on Recent Advances of Cerebral Palsy
title_sort review on recent advances of cerebral palsy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356840/
https://www.ncbi.nlm.nih.gov/pubmed/35941906
http://dx.doi.org/10.1155/2022/2622310
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