mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant

The SARS-CoV-2 Omicron variant evades vaccine-induced immunity. While a booster dose of ancestral mRNA vaccines effectively elicits neutralizing antibodies against variants, its efficacy against Omicron in older adults, who are at the greatest risk of severe disease, is not fully elucidated. Here, w...

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Detalles Bibliográficos
Autores principales: Nanishi, Etsuro, McGrath, Marisa E., O’Meara, Timothy R., Barman, Soumik, Yu, Jingyou, Wan, Huahua, Dillen, Carly A., Menon, Manisha, Seo, Hyuk-Soo, Song, Kijun, Xu, Andrew Z., Sebastian, Luke, Brook, Byron, Bosco, Anna-Nicole, Borriello, Francesco, Ernst, Robert K., Barouch, Dan H., Dhe-Paganon, Sirano, Levy, Ofer, Frieman, Matthew B., Dowling, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357006/
https://www.ncbi.nlm.nih.gov/pubmed/35933439
http://dx.doi.org/10.1038/s42003-022-03765-3

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