USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING

Pattern recognition receptors (PRRs) and interferons (IFNs) serve as essential antiviral defense against SARS-CoV-2, the causative agent of the COVID-19 pandemic. Type III IFNs (IFN-λ) exhibit cell-type specific and long-lasting functions in auto-inflammation, tumorigenesis, and antiviral defense. H...

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Detalles Bibliográficos
Autores principales: Karlowitz, Rebekka, Stanifer, Megan L., Roedig, Jens, Andrieux, Geoffroy, Bojkova, Denisa, Bechtel, Marco, Smith, Sonja, Kowald, Lisa, Schubert, Ralf, Boerries, Melanie, Cinatl, Jindrich, Boulant, Steeve, van Wijk, Sjoerd J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357023/
https://www.ncbi.nlm.nih.gov/pubmed/35933402
http://dx.doi.org/10.1038/s41419-022-05124-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357023/
https://www.ncbi.nlm.nih.gov/pubmed/35933402
http://dx.doi.org/10.1038/s41419-022-05124-w

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