Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

Defining the complex role of the microbiome in colorectal cancer and the discovery of novel, protumorigenic microbes are areas of active investigation. In the present study, culturing and reassociation experiments revealed that toxigenic strains of Clostridioides difficile drove the tumorigenic phen...

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Detalles Bibliográficos
Autores principales: Drewes, Julia L., Chen, Jie, Markham, Nicholas O., Knippel, Reece J., Domingue, Jada C., Tam, Ada J., Chan, June L., Kim, Lana, McMann, Madison, Stevens, Courtney, Dejea, Christine M., Tomkovich, Sarah, Michel, John, White, James R., Mohammad, Fuad, Campodónico, Victoria L., Heiser, Cody N., Wu, Xinqun, Wu, Shaoguang, Ding, Hua, Simner, Patricia, Carroll, Karen, Shrubsole, Martha J., Anders, Robert A., Walk, Seth T., Jobin, Christian, Wan, Fengyi, Coffey, Robert J., Housseau, Franck, Lau, Ken S., Sears, Cynthia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Briefs
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357196/
https://www.ncbi.nlm.nih.gov/pubmed/35678528
http://dx.doi.org/10.1158/2159-8290.CD-21-1273

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