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Total Synthesis of Kibdelomycin

A modular total synthesis of kibdelomycin is disclosed that should enable structure–activity relationship (SAR) studies of this interesting class of antibiotics. The route uses simple building blocks and addresses lingering questions about its structural assignment and relationship to amycolamicin,...

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Detalles Bibliográficos
Autores principales: He, Chi, Wang, Yu, Bi, Cheng, Peters, David S., Gallagher, Timothy J., Teske, Johannes, Chen, Jason S., Corsetti, Rachel, D'Onofrio, Anthony, Lewis, Kim, Baran, Phil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357209/
https://www.ncbi.nlm.nih.gov/pubmed/35704446
http://dx.doi.org/10.1002/anie.202206183