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HMGB1-activatied NLRP3 inflammasome induces thrombocytopenia in heatstroke rat

BACKGROUND: Thrombocytopenia, an early common complication in heatstroke (HS), has been widely considered as a mortality predictor of HS. The mechanism underlying thrombocytopenia in HS remains unknown. It is not known whether NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome i...

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Detalles Bibliográficos
Autores principales:	Yin, Huimei, Wu, Ming, Lu, Yong, Wu, Xinghui, Yu, BaoJun, Chen, Ronglin, Lu, JieFu, Tong, Huasheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Emergency and Critical Care
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357367/ https://www.ncbi.nlm.nih.gov/pubmed/35945940 http://dx.doi.org/10.7717/peerj.13799

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