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Trimetazidine Reduces Cardiac Fibrosis in Rats by Inhibiting NOX2-Mediated Endothelial-to-Mesenchymal Transition

PURPOSE: Endothelial-to-mesenchymal transition (EndMT) is an important mechanism underlying cardiac fibrosis. The anti-ischemic drug trimetazidine (TMZ) is reportedly useful in ventricular remodeling and associated with NADPH oxidase (NOX) 2. This study aimed to investigate the possible effect of TM...

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Detalles Bibliográficos
Autores principales:	Chen, Xingxing, Xia, Xue, Dong, Tiancheng, Lin, Zhiwei, Du, Leilei, Zhou, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357386/ https://www.ncbi.nlm.nih.gov/pubmed/35946039 http://dx.doi.org/10.2147/DDDT.S360283

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