Assessment of Cariogenicity by pH-value Decrement of Plaque Solution with Four Infant Milk Formulas: An In Vitro Study

INTRODUCTION: People all over the world use a wide variety of infant formulas to nourish the infants. Recent studies demonstrated the high caries-inducing potential of infant formulas. This indicates a need for awareness toward the possible role of the infant formulas in the etiology of early childhood caries (ECC). AIM: The present study was undertaken to evaluate and comparatively assess the change in plaque pH solutions after fermenting four commonly used infant milk formulas. MATERIALS AND METHODS: This simple randomized study was carried out on 40 healthy children aged 4–6 years old. The children received full-mouth prophylaxis before examination. They were asked not to implicate oral hygiene for 24 hours and not to have anything at least 2 hours prior the study. Supragingival plaque from the buccal surface of posterior teeth was collected using a Hu-Friedy's curette. Four commonly used infant milk formulas were prepared and given to children for rinsing. The pH of plaque samples were measured at 30 and 60 minutes at 37°C. RESULTS: The present study showed that all of the four infant milk formulas decreased the mean pH values in plaque solutions significantly after 30 and 60 minutes of preparation. CONCLUSION: Our results showed that the plaque pH varied in response to the oral rinsing with the various infant formulas and most of infant formulas were able to reduce the pH significantly below the pH before the rinse. Based upon this study further evaluation of the cariogenicity of infant formulas is recommended. HOW TO CITE THIS ARTICLE: Pandey A, Pathivada L, Kajapuram P, et al. Assessment of Cariogenicity by pH-value Decrement of Plaque Solution with Four Infant Milk Formulas: An In Vitro Study. Int J Clin Pediatr Dent 2022;15(3):263-266.