Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress

We sought to unravel pathomechanisms of the transition of maladaptive right ventricular (RV) remodeling to right heart failure (RHF) upon pressure overload. Exposure of C57BL/6J and C57BL/6N mice to pulmonary artery banding disclosed a tight relation of structural remodeling with afterload, but a di...

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Detalles Bibliográficos
Autores principales: Müller, Marion, Bischof, Cornelius, Kapries, Torben, Wollnitza, Sophie, Liechty, Chiara, Geißen, Simon, Schubert, Torben, Opacic, Dragan, Gerçek, Muhammed, Fortmeier, Vera, Dumitrescu, Daniel, Schlomann, Uwe, Sydykov, Akylbek, Petrovic, Aleksandar, Gnatzy-Feik, Leoni, Milting, Hendrik, Schermuly, Ralph T., Friedrichs, Kai, Rudolph, Volker, Klinke, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357563/
https://www.ncbi.nlm.nih.gov/pubmed/35958691
http://dx.doi.org/10.1016/j.jacbts.2022.02.018

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