Cargando…

Reverse Reaction of Nicotinamide Nucleotide Transhydrogenase Promotes ROS Production and Contributes to Right Ventricular Failure

[Figure: see text]

Detalles Bibliográficos
Autores principales:	Lemay, Sarah-Eve, Boucherat, Olivier, Bonnet, Sébastien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research - Preclinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357571/ https://www.ncbi.nlm.nih.gov/pubmed/35958692 http://dx.doi.org/10.1016/j.jacbts.2022.03.015

Ejemplares similares

PARP1-PKM2 Axis Mediates Right Ventricular Failure Associated With Pulmonary Arterial Hypertension
por: Shimauchi, Tsukasa, et al.
Publicado: (2022)

Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II
por: Rao, K.N. Shashanka, et al.
Publicado: (2020)

Proton-Translocating Nicotinamide Nucleotide Transhydrogenase: A Structural Perspective
por: Zhang, Qinghai, et al.
Publicado: (2017)

Mutations in Nicotinamide Nucleotide Transhydrogenase (NNT) cause familial glucocorticoid deficiency
por: Meimaridou, Eirini, et al.
Publicado: (2012)

Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma
por: Chortis, Vasileios, et al.
Publicado: (2018)

Transcription Levels of nicotinamide nucleotide transhydrogenase and Its Antisense in Breast Cancer Samples
por: Saleh Gargari, Soraya, et al.
Publicado: (2019)

Energy transfer between the nicotinamide nucleotide transhydrogenase and ATP synthase of Escherichia coli
por: Graf, Simone Sandra, et al.
Publicado: (2021)

Right Ventricular Dysfunction in Pulmonary Hypertension: Is Resistin a Promising Target?
por: Lemay, Sarah‐Eve, et al.
Publicado: (2023)

Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation
por: Ho, Hung-Yao, et al.
Publicado: (2017)

The Combination of Niacinamide, Vitamin C, and PDRN Mitigates Melanogenesis by Modulating Nicotinamide Nucleotide Transhydrogenase
por: Park, Hyun Jun, et al.
Publicado: (2022)

Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2
por: Parker, Nadeene, et al.
Publicado: (2009)

Nicotinamide nucleotide transhydrogenase-mediated redox homeostasis promotes tumor growth and metastasis in gastric cancer
por: Li, Shuai, et al.
Publicado: (2018)

Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function
por: Ward, Nathan P., et al.
Publicado: (2020)

Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism
por: McCambridge, Grace, et al.
Publicado: (2019)

SAT343 Nicotinamide Nucleotide Transhydrogenase (NNT)-related Familial Glucocorticoid Deficiency: More Than Adrenal Insufficiency
por: Shanker, Anita, et al.
Publicado: (2023)

Three‐Dimensional Model of Human Nicotinamide Nucleotide Transhydrogenase (NNT) and Sequence‐Structure Analysis of its Disease‐Causing Variations
por: Metherell, Louise A, et al.
Publicado: (2016)

Upregulated expression of LncRNA nicotinamide nucleotide transhydrogenase antisense RNA 1 is correlated with unfavorable clinical outcomes in cancers
por: Zhang, Chenghao, et al.
Publicado: (2020)

Factors Influencing Mitochondrial Function as a Key Mediator of Glucose-Induced Insulin Release: Highlighting Nicotinamide Nucleotide Transhydrogenase
por: Aghelan, Zahra, et al.
Publicado: (2020)

Ligand binding and conformational dynamics of the E. coli nicotinamide nucleotide transhydrogenase revealed by hydrogen/deuterium exchange mass spectrometry
por: Zöller, Jonathan, et al.
Publicado: (2022)

Impact of a novel homozygous mutation in nicotinamide nucleotide transhydrogenase on mitochondrial DNA integrity in a case of familial glucocorticoid deficiency
por: Fujisawa, Yasuko, et al.
Publicado: (2014)

Loss of Nicotinamide nucleotide transhydrogenase sensitizes embryos to ethanol-induced neural crest and neural apoptosis via generation of reactive oxygen species
por: Mazumdar, Rayna, et al.
Publicado: (2023)

ODP055 The methylation pattern of a unique Bilateral para-overian Adrenal Rest Tumor in a girl with Nicotinamide Nucleotide Transhydrogenase mutation
por: Cahn, Ranit, et al.
Publicado: (2022)

Testicular impairment in Primary Adrenal Insufficiency caused by Nicotinamide Nucleotide Transhydrogenase (NNT) deficiency - a case report: implication of oxidative stress and importance of fertility preservation
por: Ferreux, Lucile, et al.
Publicado: (2023)

Fetal Gene Reactivation in Pulmonary Arterial Hypertension: GOOD, BAD, or BOTH?
por: Lemay, Sarah-Eve, et al.
Publicado: (2021)

Pleiotropic Effects of Pyruvate Kinase M2 in Right Ventricular Failure and Pulmonary Arterial Hypertension
por: Christou, Helen
Publicado: (2022)

A conserved sequence motif in the Escherichia coli soluble FAD-containing pyridine nucleotide transhydrogenase is important for reaction efficiency
por: Partipilo, Michele, et al.
Publicado: (2022)

Nicotinamide Mononucleotide Alleviates Cardiomyopathy Phenotypes Caused by Short-Chain Enoyl-Coa Hydratase 1 Deficiency
por: Cai, Ke, et al.
Publicado: (2022)

Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension
por: da Silva Gonçalves Bos, Denielli, et al.
Publicado: (2017)

Successful Reconstruction of the Right Ventricular Outflow Tract by Implantation of Thymus Stem Cell Engineered Graft in Growing Swine
por: Albertario, Ambra, et al.
Publicado: (2019)

Effects of 20-Hydroxyecdysone on the Reversible Mitochondrial Transhydrogenase in the Tobacco Hornworm, Manduca sexta
por: Vandock, Kurt P., et al.
Publicado: (2013)

Glucagon-Like Peptide-1–Mediated Cardioprotection Does Not Reduce Right Ventricular Stunning and Cumulative Ischemic Dysfunction After Coronary Balloon Occlusion
por: Giblett, Joel P., et al.
Publicado: (2019)

Device-Based Ventricular Reverse Remodeling: A Multimechanistic Therapeutic Strategy
por: Alkhunaizi, Fatimah A., et al.
Publicado: (2023)

A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production
por: Maria, Durvanei Augusto, et al.
Publicado: (2012)

Entrectinib resistance mechanisms in ROS1-rearranged non-small cell lung cancer
por: Ku, Bo Mi, et al.
Publicado: (2019)

Cathepsin A Mediates Ventricular Remote Remodeling and Atrial Cardiomyopathy in Rats With Ventricular Ischemia/Reperfusion
por: Hohl, Mathias, et al.
Publicado: (2019)

A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma
por: Kyriakou, Sotiris, et al.
Publicado: (2021)

Revisiting the Role for HIF Stabilizers in Bronchopulmonary Dysplasia
por: Boucherat, Olivier, et al.
Publicado: (2020)

Percutaneous Chordae Mitral Repair: Is it the Right Way to Fix Mitral Regurgitation?
por: Modine, Thomas, et al.
Publicado: (2020)

Changes in Myocardial Microstructure and Mechanics With Progressive Left Ventricular Pressure Overload
por: Torres, William M., et al.
Publicado: (2020)

Adeno-Associated Virus Serotype 9–Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts With Left Ventricular Dysfunction Secondary to a Myocardial Infarction
por: Knezevic, Tijana, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_v31ut0huqoko8bqq6mi2smjk7i