Cargando…

Sildenafil improves radiation‐induced oral mucositis by attenuating oxidative stress, NF‐κB, ERK and JNK signalling pathways

Radiation‐induced oral mucositis is a common and dose‐limiting complication of head and neck radiotherapy with no effective treatment. Previous studies revealed that sildenafil, a phosphodiesterase 5 inhibitor, has anti‐inflammatory and anti‐cancer effects. In this study, we investigated the effect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ala, Moein, Mohammad Jafari, Razieh, Ala, Mahan, Hejazi, Sedigheh Marjaneh, Tavangar, Seyed Mohammad, Mahdavi, Seied Rabi, Dehpour, Ahmad Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357636/ https://www.ncbi.nlm.nih.gov/pubmed/35810384 http://dx.doi.org/10.1111/jcmm.17480

Ejemplares similares

Empagliflozin Enhances Autophagy, Mitochondrial Biogenesis, and Antioxidant Defense and Ameliorates Renal Ischemia/Reperfusion in Nondiabetic Rats
por: Ala, Moein, et al.
Publicado: (2022)

The antidepressant effects of GM-CSF are mediated by the reduction of TLR4/NF-ĸB-induced IDO expression
por: Hemmati, Sara, et al.
Publicado: (2019)

Breathing-induced Errors in Quantification and Description of Dominant Intra-Prostatic Lesions (Dils) in PET Images: A Simulation Study by Means of The 4D NCAT Phantom
por: Bamneshin, Khadijeh, et al.
Publicado: (2022)

Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
por: Kheraldine, Hadeel, et al.
Publicado: (2021)

The Role of Radiofrequency Hyperthermia in The Radiosensitization of A Human Prostate Cancer Cell Line
por: Janati Esfahani, Azam, et al.
Publicado: (2017)

Neural Network Performance Evaluation of Simulated and Genuine Head-and-Neck Computed Tomography Images to Reduce Metal Artifacts
por: Khaleghi, Goli, et al.
Publicado: (2022)

Evaluation of Dose-Painting in the Dominant Intraprostatic Lesions by Radiobiological Parameters using (68)Ga- PSMA PET/CT
por: Bamneshin, Khadijeh, et al.
Publicado: (2022)

Target Sestrin2 to Rescue the Damaged Organ: Mechanistic Insight into Its Function
por: Ala, Moein, et al.
Publicado: (2021)

The Footprint of Kynurenine Pathway in Cardiovascular Diseases
por: Ala, Moein, et al.
Publicado: (2022)

Effect of sildenafil citrate on endometrial preparation and outcome of frozen-thawed embryo transfer cycles: a randomized clinical trial
por: Dehghani Firouzabadi, Razieh, et al.
Publicado: (2013)

Comparison of IORT (Radical and Boost Dose) and EBRT in Terms of Disease-Free Survival and Overall Survival according to Demographic, Pathologic, and Biological Factors in Patients with Breast Cancer
por: Hashemi, Solmaz, et al.
Publicado: (2021)

Clinical effects of rectal retractor application in prostate cancer radiotherapy
por: Arefpour, Amir Mohammad, et al.
Publicado: (2021)

Novel Nitrogen-Based Chalcone Analogs Provoke Substantial Apoptosis in HER2-Positive Human Breast Cancer Cells via JNK and ERK1/ERK2 Signaling Pathways
por: Rizeq, Balsam, et al.
Publicado: (2021)

Outcome of hypofractionated breast irradiation and intraoperative electron boost in early breast cancer: A randomized non‐inferiority clinical trial
por: Fadavi, Pedram, et al.
Publicado: (2021)

Enhanced DNA Damages of Human Prostate Cancer Cells Induced by Radiofrequency Capacitive Hyperthermia Pre- and Post X-rays: 6 MV versus 15 MV
por: Mahdavi, Seied Rabi, et al.
Publicado: (2017)

Investigating dose homogeneity in radiotherapy of oral cancers in the presence of a dental implant system: an in vitro phantom study
por: Khaleghi, Goli, et al.
Publicado: (2021)

Target c-Myc to treat pancreatic cancer
por: Ala, Moein
Publicado: (2022)

Sestrin2 in cancer: a foe or a friend?
por: Ala, Moein
Publicado: (2022)

Sestrin2 Signaling Pathway Regulates Podocyte Biology and Protects against Diabetic Nephropathy
por: Ala, Moein
Publicado: (2023)

Deep Learning-based Non-rigid Image Registration for High-dose Rate Brachytherapy in Inter-fraction Cervical Cancer
por: Salehi, Mohammad, et al.
Publicado: (2022)

Application of rectal retractor for postprostatectomy salvage radiotherapy of prostate cancer: A case report and literature review
por: Ghaffari, Hamed, et al.
Publicado: (2019)

Sensitivity Uniformity Ratio as a New Index to Optimize the Scanning Geometry for Fluorescent Molecular Tomography
por: Ebrahimpour, Anita, et al.
Publicado: (2019)

Sensitivity Laplacian Ratio-Based Optimization of the Projection Selection for Diffuse Optical Tomography
por: Ebrahimpour, Anita, et al.
Publicado: (2020)

The ERK and JNK pathways in the regulation of metabolic reprogramming
por: Papa, Salvatore, et al.
Publicado: (2018)

Anticonvulsant effects of ivermectin on pentylenetetrazole- and maximal electroshock-induced seizures in mice: the role of GABAergic system and K(ATP) channels
por: Manavi, Mohammad Amin, et al.
Publicado: (2022)

The Scatter Search Based Algorithm for Beam Angle Optimization in Intensity-Modulated Radiation Therapy
por: Ghanbarzadeh, Ali, et al.
Publicado: (2018)

The Relationship between Lung and Heart Two-Dimensional Parameters and Three-Dimensional Dose-Volume Data in Adjuvant Radiotherapy for Breast Cancer
por: Fadavi, Pedram, et al.
Publicado: (2022)

Meclizine moderates lipopolysaccharide-induced neuroinflammation in mice through the regulation of AKT/ NF-κβ/ERK/JNK signaling pathway
por: Mostafa, Rasha E., et al.
Publicado: (2023)

The effect of spinally administered WIN 55,212-2, a cannabinoid agonist, on thermal pain sensitivity in diabetic rats
por: Jahanabadi, Samane, et al.
Publicado: (2016)

Target Motion Management in Breast Cancer Radiation Therapy
por: Piruzan, Elham, et al.
Publicado: (2021)

Comparison of dosimetric characteristics of physical wedge and enhanced dynamic wedge in inhomogeneous medium using Monte Carlo simulations
por: Mahdavi, Seied Rabi, et al.
Publicado: (2021)

High-Dose-Rate (192)Ir Brachytherapy Dose Verification: A Phantom Study
por: Nikoofar, Alireza, et al.
Publicado: (2015)

An analytical model to determine interseed attenuation effect in low‐dose‐rate brachytherapy
por: Safigholi, Habib, et al.
Publicado: (2013)

Why sildenafil and sildenafil citrate monohydrate crystals are not stable?
por: Sawatdee, Somchai, et al.
Publicado: (2015)

Peritonitis as the first presentation of systemic lupus erythematous: a case report
por: Kheyri, Zahedin, et al.
Publicado: (2021)

Genome- and Exome-Wide Association Studies Revealed Candidate Genes Associated with DaTscan Imaging Features
por: Yaghoobi, Arash, et al.
Publicado: (2023)

ERK and JNK Activation is Essential for Oncogenic Transformation by v-Rel
por: Kralova, Jarmila, et al.
Publicado: (2010)

JNK, p38, ERK, and SGK1 Inhibitors in Cancer
por: Cicenas, Jonas, et al.
Publicado: (2017)

Effect of hydroxychloroquine on prevention of COVID-19 virus infection among healthcare professionals: a structured summary of a study protocol for a randomised controlled trial
por: Pirjani, Reihaneh, et al.
Publicado: (2020)

Fiducial markers in prostate cancer image-guided radiotherapy
por: Ghaffari, Hamed, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8ph71ohhp7qamospl8tu9ie0dr