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Re-Expression of Tafazzin Isoforms in TAZ-Deficient C6 Glioma Cells Restores Cardiolipin Composition but Not Proliferation Rate and Alterations in Gene Expression

Tafazzin—an acyltransferase—is involved in cardiolipin (CL) remodeling. CL is associated with mitochondrial function, structure and more recently with cell proliferation. Various tafazzin isoforms exist in humans. The role of these isoforms in cardiolipin remodeling is unknown. Aim of this study was...

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Detalles Bibliográficos
Autores principales: Jagirdar, Gayatri, Elsner, Matthias, Scharf, Christian, Simm, Stefan, Borucki, Katrin, Peter, Daniela, Lalk, Michael, Methling, Karen, Linnebacher, Michael, Krohn, Mathias, Wolke, Carmen, Lendeckel, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358009/
https://www.ncbi.nlm.nih.gov/pubmed/35957687
http://dx.doi.org/10.3389/fgene.2022.931017