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A multi-organ-on-chip to recapitulate the infiltration and the cytotoxic activity of circulating NK cells in 3D matrix-based tumor model

The success of immunotherapeutic approaches strictly depends on the immune cells interaction with cancer cells. While conventional in vitro cell cultures under-represent the complexity and dynamic crosstalk of the tumor microenvironment, animal models do not allow deciphering the anti-tumor activity...

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Detalles Bibliográficos
Autores principales:	Marzagalli, Monica, Pelizzoni, Giorgia, Fedi, Arianna, Vitale, Chiara, Fontana, Fabrizio, Bruno, Silvia, Poggi, Alessandro, Dondero, Alessandra, Aiello, Maurizio, Castriconi, Roberta, Bottino, Cristina, Scaglione, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358021/ https://www.ncbi.nlm.nih.gov/pubmed/35957642 http://dx.doi.org/10.3389/fbioe.2022.945149

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