Cargando…

TMbed: transmembrane proteins predicted through language model embeddings

BACKGROUND: Despite the immense importance of transmembrane proteins (TMP) for molecular biology and medicine, experimental 3D structures for TMPs remain about 4–5 times underrepresented compared to non-TMPs. Today’s top methods such as AlphaFold2 accurately predict 3D structures for many TMPs, but...

Descripción completa

Detalles Bibliográficos
Autores principales: Bernhofer, Michael, Rost, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358067/
https://www.ncbi.nlm.nih.gov/pubmed/35941534
http://dx.doi.org/10.1186/s12859-022-04873-x