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Qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy

OBJECTIVE: This research sought to explore health care providers’ (HCPs) experiences of delivering the first US Food and Drug Administration (FDA) and European Commission (EC) approved peanut oral immunotherapy (peanut OIT; Palforzia). Semi-structured qualitative interviews with HCPs who had initiat...

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Autores principales: Anagnostou, Aikaterini, Lawrence, Claire, Tilles, Stephen A., Laubach, Susan, Donelson, Sarah M., Yassine, Mohamed, Nowak-Wegrzyn, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358114/
https://www.ncbi.nlm.nih.gov/pubmed/35941597
http://dx.doi.org/10.1186/s13104-022-06161-6
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author Anagnostou, Aikaterini
Lawrence, Claire
Tilles, Stephen A.
Laubach, Susan
Donelson, Sarah M.
Yassine, Mohamed
Nowak-Wegrzyn, Anna
author_facet Anagnostou, Aikaterini
Lawrence, Claire
Tilles, Stephen A.
Laubach, Susan
Donelson, Sarah M.
Yassine, Mohamed
Nowak-Wegrzyn, Anna
author_sort Anagnostou, Aikaterini
collection PubMed
description OBJECTIVE: This research sought to explore health care providers’ (HCPs) experiences of delivering the first US Food and Drug Administration (FDA) and European Commission (EC) approved peanut oral immunotherapy (peanut OIT; Palforzia). Semi-structured qualitative interviews with HCPs who had initiated treatment with ≥ 3 patients in the first nine months following FDA approval sought to identify challenges faced and successful implementation strategies. RESULTS: Eight allergists and three nurse practitioners from eight sites based in the United States participated. The HCPs included in this research were motivated to implement this novel treatment, however, entered the process with some reservations. HCPs described how successful implementation of peanut OIT requires them to be thoughtful about their clinic’s abilities to integrate complex, time-consuming treatments into their daily practice. Prior experience of OIT was deemed beneficial, but not essential for implementation and learning from others’ experience was suggested as a way of helping new prescribers overcome perceived and actual implementation challenges. Delivering licensed peanut OIT during the COVID-19 pandemic posed both challenges and unexpected opportunities for implementation. The experiences described have the potential to benefit the wider allergy community by providing practical solutions, successful implementation strategies and opportunities to enhance training and resources. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-022-06161-6.
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spelling pubmed-93581142022-08-09 Qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy Anagnostou, Aikaterini Lawrence, Claire Tilles, Stephen A. Laubach, Susan Donelson, Sarah M. Yassine, Mohamed Nowak-Wegrzyn, Anna BMC Res Notes Research Note OBJECTIVE: This research sought to explore health care providers’ (HCPs) experiences of delivering the first US Food and Drug Administration (FDA) and European Commission (EC) approved peanut oral immunotherapy (peanut OIT; Palforzia). Semi-structured qualitative interviews with HCPs who had initiated treatment with ≥ 3 patients in the first nine months following FDA approval sought to identify challenges faced and successful implementation strategies. RESULTS: Eight allergists and three nurse practitioners from eight sites based in the United States participated. The HCPs included in this research were motivated to implement this novel treatment, however, entered the process with some reservations. HCPs described how successful implementation of peanut OIT requires them to be thoughtful about their clinic’s abilities to integrate complex, time-consuming treatments into their daily practice. Prior experience of OIT was deemed beneficial, but not essential for implementation and learning from others’ experience was suggested as a way of helping new prescribers overcome perceived and actual implementation challenges. Delivering licensed peanut OIT during the COVID-19 pandemic posed both challenges and unexpected opportunities for implementation. The experiences described have the potential to benefit the wider allergy community by providing practical solutions, successful implementation strategies and opportunities to enhance training and resources. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-022-06161-6. BioMed Central 2022-08-08 /pmc/articles/PMC9358114/ /pubmed/35941597 http://dx.doi.org/10.1186/s13104-022-06161-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Anagnostou, Aikaterini
Lawrence, Claire
Tilles, Stephen A.
Laubach, Susan
Donelson, Sarah M.
Yassine, Mohamed
Nowak-Wegrzyn, Anna
Qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy
title Qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy
title_full Qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy
title_fullStr Qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy
title_full_unstemmed Qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy
title_short Qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy
title_sort qualitative interviews to understand health care providers’ experiences of prescribing licensed peanut oral immunotherapy
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358114/
https://www.ncbi.nlm.nih.gov/pubmed/35941597
http://dx.doi.org/10.1186/s13104-022-06161-6
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